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Tanya Simuni Selected Research

Isradipine (Dynacirc)

1/2022Re-Analysis of the STEADY-PD II Trial-Evidence for Slowing the Progression of Parkinson's Disease.
10/2021Novel Approach to Movement Disorder Society-Unified Parkinson's Disease Rating Scale Monitoring in Clinical Trials: Longitudinal Item Response Theory Models.
1/2021Design of a virtual longitudinal observational study in Parkinson's disease (AT-HOME PD).
1/2021Isradipine plasma pharmacokinetics and exposure-response in early Parkinson's disease.
11/2020Cognitive impairment in Parkinson's disease: Associations between subjective and objective cognitive decline in a large longitudinal study.
1/2017A novel design of a Phase III trial of isradipine in early Parkinson disease (STEADY-PD III).
12/2010Tolerability of isradipine in early Parkinson's disease: a pilot dose escalation study.

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Tanya Simuni Research Topics

Disease

59Parkinson Disease (Parkinson's Disease)
01/2022 - 04/2002
9Disease Progression
01/2022 - 11/2011
7Movement Disorders (Movement Disorder)
10/2021 - 04/2014
6Tremor (Tremors)
01/2022 - 11/2011
5Parkinsonian Disorders (Parkinsonism)
01/2019 - 12/2010
4Alzheimer Disease (Alzheimer's Disease)
01/2020 - 11/2011
3Psychotic Disorders (Schizoaffective Disorder)
10/2019 - 11/2017
3Sleepiness
01/2017 - 04/2014
2Hypokinesia (Bradykinesia)
01/2021 - 12/2018
2REM Sleep Behavior Disorder
01/2021 - 01/2018
2Neurobehavioral Manifestations
11/2020 - 01/2014
2Neurodegenerative Diseases (Neurodegenerative Disease)
11/2020 - 01/2017
2Disorders of Excessive Somnolence (Hypersomnia)
01/2020 - 04/2014
2Cognitive Dysfunction
01/2019 - 01/2017
2Hallucinations (Hallucination)
11/2017 - 11/2012
2Essential Tremor (Essential Tremors)
01/2015 - 11/2011
2Edema (Dropsy)
11/2012 - 12/2010
1Panic Disorder (Panic Attack)
01/2022
1Confusion (Bewilderment)
01/2022
1Injection Site Reaction
11/2021
1Kidney Calculi (Kidney Stone)
01/2021
1Synucleinopathies
01/2021
1Disruptive, Impulse Control, and Conduct Disorders (Kleptomania)
11/2019
1Anosmia
01/2018
1Mitochondrial Diseases (Mitochondrial Disease)
12/2017
1Atrophy
01/2017
1Drug-Induced Dyskinesia (Dyskinesia, Drug Induced)
04/2016
1Fatigue
01/2016
1Inflammation (Inflammations)
01/2015
1Dementia (Dementias)
11/2011
1Lewy Body Disease (Lewy Body Dementia)
11/2011
1Hypertension (High Blood Pressure)
12/2010
1Dizziness (Lightheadedness)
12/2010

Drug/Important Bio-Agent (IBA)

15Biomarkers (Surrogate Marker)IBA
01/2021 - 10/2013
7Isradipine (Dynacirc)FDA LinkGeneric
01/2022 - 12/2010
6Pharmaceutical PreparationsIBA
10/2021 - 11/2011
6Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
01/2021 - 11/2011
5Levodopa (L Dopa)FDA LinkGeneric
01/2022 - 01/2015
5Biological ProductsIBA
01/2021 - 09/2015
4Glucosylceramidase (Glucocerebrosidase)IBA
01/2022 - 01/2018
4Antipsychotic Agents (Antipsychotics)IBA
01/2020 - 11/2017
3Uric Acid (Urate)IBA
01/2022 - 01/2020
3InosineFDA Link
01/2022 - 01/2021
3alpha-SynucleinIBA
01/2021 - 09/2015
3pimavanserinIBA
10/2019 - 11/2017
21,4-dihydropyridine (dihydropyridine)IBA
01/2021 - 12/2010
2Leucine (L-Leucine)FDA Link
01/2020 - 01/2018
2Hypnotics and Sedatives (Sedatives)IBA
01/2020 - 09/2015
2Phosphotransferases (Kinase)IBA
01/2020 - 01/2018
2SynucleinsIBA
01/2019 - 10/2013
2Amyloid (Amyloid Fibrils)IBA
01/2017 - 10/2013
1Glucosylceramides (Glucocerebrosides)IBA
01/2022
1venglustatIBA
01/2022
1GlycosphingolipidsIBA
01/2022
1Carbidopa (Lodosyn)FDA LinkGeneric
11/2021
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2021
1nilotinibFDA Link
01/2021
1Monoamine Oxidase (MAO)IBA
01/2021
1Proteins (Proteins, Gene)FDA Link
01/2021
1Neuroprotective AgentsIBA
01/2021
1Calcium Channels (Calcium Channel)IBA
01/2021
1Cholinergic Antagonists (Anticholinergics)IBA
01/2020
1Anti-Anxiety Agents (Anxiolytics)IBA
01/2020
1Antidepressive Agents (Antidepressants)IBA
01/2020
1amsonic acid (DAS)IBA
11/2019
1Dopamine Agonists (Dopamine Agonist)IBA
11/2019
1Clozapine (Clozaril)FDA LinkGeneric
12/2018
1Quetiapine Fumarate (Seroquel)FDA Link
12/2018
1CalciumIBA
12/2017
1Dopamine (Intropin)FDA LinkGeneric
01/2017
1Medical MarijuanaIBA
01/2017
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2017
1valylvaline (Val-Val)IBA
01/2017
1Amyloid beta-PeptidesIBA
01/2017
1CreatineIBA
02/2015
1ThiazolidinedionesIBA
02/2015
1Pioglitazone (Actos)FDA Link
01/2015
1Interleukin-6 (Interleukin 6)IBA
01/2015
18-Hydroxy-2'-DeoxyguanosineIBA
01/2015
1Hypoglycemic Agents (Hypoglycemics)IBA
01/2015
1MelatoninIBA
04/2014
1Exenatide (Byetta)FDA Link
01/2014
1Glucagon-Like Peptide-1 ReceptorIBA
01/2014
1tau Proteins (tau Protein)IBA
10/2013
1propylene diquat (PDQ(+))IBA
09/2013
1Amantadine (Aman)FDA LinkGeneric
11/2012
1ioflupaneIBA
11/2011
1LigandsIBA
11/2011
1Calcium Channel Blockers (Blockers, Calcium Channel)IBA
12/2010

Therapy/Procedure

15Therapeutics
01/2022 - 04/2002
4Deep Brain Stimulation
11/2014 - 09/2003
3Activities of Daily Living (ADL)
01/2019 - 01/2015
2Precision Medicine
01/2021 - 01/2020
1Drug Therapy (Chemotherapy)
01/2021
1Physical Therapy Modalities (Physical Therapy Technique)
12/2019
1Wearable Electronic Devices
01/2019
1Palliative Care (Palliative Therapy)
01/2019
1Behavior Control
01/2016
1Complementary Therapies (Alternative Medicine)
10/2014
1Drug Tapering
12/2010